Nice build for an almost all printed Z-axis for a CNC. Not so sure I would do this over building one from other materials. I would be a bit worried about the flex on the plastic. The author geared this for use with an arduino, but it doesn’t matter what micro-controller you use.
http://www.instructables.com/id/CNC-Z-AXIS-for-ARDUINO-projects-or-small-router-pr/